[English translation]

To make a wine for use against the malady of the stone.
Take 3 handfuls of cinquefoil leaves with the roots and 5 handfuls of the roots of couch grass, well washed and clean, 2 handfuls of saxifrage, a full bowl of whole red berries of winter cherry and 2 cut lemons. The herbs should be cut finely. Put everything in a little bag of fine, loosely-knit linen tied with a thread to the top of a wine barrel and fill this barrel with must of good, pure white wine that has not been fermented and let it ferment for 1 month or more in the barrel with the little bag in it and every evening fill it up with some must so that it heats better and purifies itself and throws down all the bad lees. When it will not ferment any more and becomes cold and clear, remove the little bag and strain the wine carefully so it does not become turbid. Then return it to the barrel and stopper it well at the top so it keeps better. When it seems to you that you feel the pain of the stone in the bladder or in the kidney or have some other difficulty with urination, drink a glass of this wine early in the morning, staying in bed and reposing for at least 2 hours. Depending on the improvement that you feel, drink it for 2 or 3 mornings and not more because it will overheat the liver. If you think that you may be drinking too much, drink it one morning and not the next so that it has less effect on you. This wine aids greatly in breaking the stone in the bladder and in the kidney and causes copious urination. You will feel the stones going out of the penis. If the effect is not rapid enough with the remedies above, it is appropriate to use some poultices or ointments on the pubic region or on the penis or kidney. Take care of yourself and eat things suited to the desired result. By doing this you will help nature recover to pristine health, with the aid of God and of Saint Cosmas and Saint Damian. You will not be the first to achieve this and you will be cured.

Another to break a stone in the bladder or the kidney and to urinate it little by little.
Take 2 drams each of cloves, galingale, millet and cinnamon, all powdered, and parsley, asparagus and saxifrage, dried and powdered, and ashes made from scorpions, and blood of goat and of hare, everything powdered and mixed. Then give one spoonful of it to drink early in the morning with white wine with sugar in it and it will help you greatly to break the stone and it will make you urinate copiously.

Another.
Take one glass of the following water in the morning and in the evening when you go to sleep. It should be warm with sugar in it and it will make you urinate a lot of gravel. Take 1 ounce each of water of radish, of butcher's broom, of asparagus, of fennel, of celery, of couch grass and of goat's rue. When you drink it, drink it rapidly and soon it will work to make you urinate the gravel gently without distress.

Another for the pain in the kidneys caused by the stone.
Take a large flask for the fire, fill it with good white wine and put therein these herbs, cut finely, that is half a handful each of mallow, watercress and pellitory and one grated radish, 1 ounce of ordinary oil and 10 cherries of winter cherry. Let the flask boil before the fire for a little. Then remove it carefully so it does not break and when it is cold strain it carefully. Give 4 ounces of it warm to the sick person with a stone or with gravel to drink early in the morning. He should stay in repose. Do this several mornings. Make more of this beverage as you have made this and if you will continue it, be sure that it will cause urination when you want and in excess.

Another, an unguent for this malady of the kidneys.
Take 3 ounces each of oil of roses and violets and myrtle, 1 ounce each of clotted goat's milk, powdered deer horn and butter, ½ ounce of camphor and 2 ounces of clean wax. Mix everything thoroughly in a pot on a slow fire and remove it from the fire before it boils too much. Put in the camphor cut finely and stir it continuously until it is cold and it will be made. Rub the kidneys in the evening with this cold and it will help you greatly. It has been tested.

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[Italian transcript]

A fare vino contra male di pietra.
Rx. del pantafilon, i cinque foglie, con le radice, m. iij, e radice di gramigna, m. v, ben lavate e nette e saxifragia m. ij et li graneli rossi deli anchechingi una piena scudella cossi intieri et 2 limoni taliati et l’erbe taliate minute et meti ogni cosa in uno sachettino de lino sottile e rado legalo con un filo di sopra la bocca del barile et empirai el ditto barile di mosto de vin biancho bono puro che non abia bolito et lasselo bolire per un mese o piu inel barile col sachettino drento et ogni sera lo reimpie con del ditto mosto accio che meglio bolla e si purifichi e butta fora tutte le cative feccie. Et piu chel non bolira e sara freddo e chiaro, cavene il sachetto e colalo ligiermente che non se intorbedi. Poi ritornalo in quello barile et turalo bene con di sopra la sua cenerata che meglio si conserva. Et quando a te parera di sentirti dolore di pietra inella vessicha o inele rene overo qualche altro diffetto circha ha l’orinare et tu beverai un bichiere del ditto vino la matina per tempo, stando in letto et riposandoti sopra al manco per 2 ore. Et secondo el miglioramento che tu ti sentirai bevene per 2 o 3 matine e non piu perche ti riscaldaria tropo il fegato et se’l ti facesse tropo danno bevene una matina si, e l’altro no, che manco danno ti fara. Et questo vino molto aiutta a corrodere la pietra in ella vissicha et inele rene et la fa pissare abondantemente et la sentirai inell ussire dela verga et se l’operare non fusse cossi presto opera de i remedii ditto di sopra confarti alcuni empiastri overo ontioni sul petenechio, sun la verga o sun le rene. Et conservarti del vivere tuo e mangiare cose aprobate a operare et facendo questo tu provocherai la natura a recuperare la prestina sanita con lo aiutto de dio et di san gosimo et damiano et operando questo non serai il primo et guarirai.
Item a fare rompere la pietra in vessiche et inele rene et farla pissare a poc a poco.
Rx. garoffani, galanga, miglio, canella fatte tutte in polvere, persemoli, sparesi, saxifragia fatte seccare et fattone polvere et cenere fatta de scorpioni et sangue di becho e di lopore, ana drame ij, et tutte in polvere et incorporate. Poi ne darai a bere uno cugiaro la matina per tempo con vino bianco con zuccaro drento e molto ti zovera a corrodere la pietra et abondantemente ti fara pissare.
Item.
Torai questa aqua uno bichiere la matina e la sera quando vai a dormire e che la sia calda con zucaro et ti fara pissare di molta ranella. Torai aqua de radice e di bruscho e di sparesi e di finochio e di appio e di gramigna et di castrachane, ana onza j, et quando la bevi, bevila con furia e presto ti operera in farti pissare amorevolmente la ranella senza passione.
Item al dolore dele rene per causa dela pietra.
Torai una inchistara da foco grande, empila de vino bianco bono et mettivi drento queste erbe tagliate minute, cioe malva, cressoni e vitriola et uno ravanello gratusato, ana m ½, e onza j olio comune et 10 cierese di alchechingi et lassa bolire la inchistara per un pezo dinanti al foco. Poi la levi destramente che non la rompi et como la e freda tu la coli sutilmente et dane a bere al difettoso di pietra o di ranella onze iiij la matina per tempo e calda e stia in riposso. Et fallo parechie matine et come ai fornita questa bevanda tu ne farai del altra et la continuerai et la ti fara pissare quanto vorai e pur troppo.
Item unguento al ditto male di reni.
Rx. olio roxato e violato e olio di mortella, ana onze iij, coaguli caprini, raspa dure di corno di cervio e butiro, ana onza j, canphora onza s, cera nova onze ij et componi ogni cosa sutilmente nel tozetto con lento foco et quando l’ai levato dal foco et chel non sia tanto bolito alora metteli la canphora taliata minuta et sempre mestando finche e freddo et sera fato. Ongeti le rene la sera cosi fredo et molto ti zovera. E provato.