005
THURSDAY, NOVEMBER 10,2005
NEWS
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Partnership forms for drug development
HEALTH
BY TRAVIS ROBINETT
trobinett@kansan.com
KANSAN STAFF WRITER
INSTITUTE PARTNERS
The University of Kansas has joined 11 other universities to research the drug-development process in hopes of lowering the price tag and the time involved in manufacturing drugs.
The new National Institute for Pharmaceutical Technology and Education, which formed on Nov. 3, is led by Charles Rutledge, vice president for research at Purdue University, KU alumnus and a former KU professor.
Karen Mahoney, spokesperson for the FDA, said that any changes pharmaceutical companies made to FDA-approved drugs had to be reviewed. To make a change, a company has to turn in an application explaining the changes so the FDA can see that the drug still serves its intended purpose. That process takes time.
Gurvich said the companies were afraid to make changes because the FDA process took so long. He said the only way to improve the process was for companies to work together with the FDA. He said the institute would help by making new technologies,
Member universities of the National Institute for Pharmaceutical Technology and Education:
The need for cheaper and faster drug development is clear. Getting a drug to the market can take 10 to 15 years and cost as much as $2 billion, said Vadim Gurvich, assistant director of the KU Center for Drug Discovery and associate director of the Institute.
University of Kansas
Duquesne University at
Illinois Institute of
Technology
Purdue University at West Lafayette
Lafayette
which could translate into lower costs, available to every company.
Mahoney said the FDA intended to do away with the applications for change with the help of the institute's research. She said she hoped the research would cut down on time.
Getting a drug to the market takes so long because pharmaceutical companies use a trial-and-error approach, Gurvich said. He said the chemical reactions used to make drugs rely on specific conditions, such as the temperature at which the drug worked best.
He said the companies tested a wide range of variables and needed to narrow that range to produce drugs faster.
Gurvich said the Institute hoped to change the old-fashioned approach for testing drug quality, which was to make the drug and then analyze it when it's finished. The institute wants to find ways to analyze the drug throughout the process so the manufacturer can make changes
University of Connecticut
University of Iowa
University of Kentucky
University of Maryland
University of Minnesota
Rutgers University at New Brunswick
Universidad de Puerto Rico de Mayaguez
Universidad de Puerto Rico of San Juan
Source: University Relations
The institute has plans to develop drug-modeling tools like those the aerospace industry uses, Gurvich said. He said aerospace scientists designed planes on computers because they had tools to predict how all the parts would behave.
during development.
"Ideally, we want to learn so much about processes during manufacturing that we can model them on computers. It's a long shot but not impossible."
Gurvich said that would require a combination of different scientific expertise.
"Twelve universities can do this," he said.
Rutledge said the universities would collaborate through a board of directors. Most of the funding for the institute was from Purdue, but each University involved would contribute $7,500, he said. The institute will seek federal funding it hopes will be authorized by the end of this year.
— Edited by Becca Evanhoe
ON CAMPUS
- The African Student Association is holding an African language fair and tea time from 2 to 4 p.m. today on the fourth floor of the Kansas Union.
executive producer of television's "The West Wing." will speak at 7:30 tonight at the Dole Institute of Politics on West Campus.
the fourth floor of the Kansas Union. Students who register will get prizes.
- The Muslim Student Association is holding the 2005 Fast-A-Thon on Tuesday. MSA invites KU students to fast during the day and eat a free lftr dinner at 5:00 p.m. at Macei's, 1031 New Hampshire St. Sign up at www.msaku.com
As part of Donate Life Week, the KU Organ Donation Awareness Coalition is holding an organ donation registration from 9 a.m. to 3 p.m. Friday on
Candice Rukes/KANSAN
- For the Dole Institute of Politics' Hollywood & Politics' lecture series, Alex Graves,
The KU marching band practices in preparation for Saturday's game against Texas. The Marching Jayhawks will travel to Austin, Texas, to perform at the halftime show. The band practices every Monday and Wednesday throughout the football season.
Preparing for the two-step
A 19-year-old KU student reported to Lawrence police damage to a vehicle's window between 6 p.m. Nov. 1 and 3:10 p.m. Nov. 3 on the 1600 block of Tennessee Street.The damage is estimated at $200.
ON THE RECORD
- A 23-year-old KU student reported to Lawrence police damage to a vehicle's windshield, hood and turn signal light between 2 a.m. and 1 p.m. Nov. 1 on the 2000 block of West Sixth Street. The damage is estimated at $900.
A 42-year-old employee of Elchus Building Services reported to Lawrence police damage to a storm window between 9 a.m. Oct. 31 and 10:30 a.m. Nov. 1 at the Sigma Nu house, 1501 Sigma Nu Place.The damage is estimated at $500.
♦ A 21-year-old KU student reported to Lawrence police the burglary of a vehicle and theft of a JVC car stereo between 10 p.m. Oct. 31 and 3:50 p.m. Nov. 3 from the 700 block of Comet Lane.The car stereo is valued at $250.
♦ An 18-year-old KU student reported to Lawrence police the theft of a Trek bicycle and other items between 3 a.m. and 1:30 p.m. Nov. 1 from the 1000 block of Monterrey Way. The bicycle is valued at $350. The items are valued at $20.
- An 18-year-old KU student reported to the KU Public Safety Office that a door lock was super glued between 3:15 and 8:15 a.m. Friday at Jayhawk Towers. The damage is estimated at $8750.
A 21-year-old KU student reported to the KU Public Safety Office both sides of a Chevrolet Cavalier scratched between 2:30 a.m. and 5:07 p.m. Friday.The damage is estimated at $1,000.
- An 18-year-old KU student reported to the KU Public Safety Office damage to a Nissan Altima between 8:30 p.m. Nov. 6 and 11 a.m. Monday in lot 112, next to Oliver Hall. The damage is estimated at $2,500.
♦ An 18-year-old KU student reported to the KU Public Safety Office the theft of a $140 Schwinn bicycle and two cable locks between 5 p.m. Oct. 25 and 11 a.m. Tuesday. The bicycle is valued at $140. The cable locks are valued at $30.
THIS WEEK ON CAMPUS
KU for Uganda
is showing the film Invisible Children at 7:00 p.m. on Saturday, November 12 in Woodruff Auditorium.
After the film, 2005 KU graduate Erin Larive will speak about her experiences in the
Ugandan war zone this summer and about how KU students can get involved in finding a peaceful solution to the conflict.
Mentoring In the Lives of Kids is an after-school volunteer program that works with 8 different elementary and junior high schools
*For only one hour a week, volunteers can tutor, be in a class, or work one-on-one with local students.
*Times are 3:30-5:00 MTRF,
1:30-5 W
*Volunteering hours and locations are very flexible. Feel free to bring your own activities and ideas to your school site.
The sky's the limit!
*Also currently looking
for a publicity co-ordinator
Contact milk@raven.cc.ku.edu or (785) 864-4072; SILC offices 410 Kansas Union
KU Student mentors provide free private lessons in musical instruments and vocal training to elementary and junior high students attending lower socio-economic schools.
Mentoring sessions take place every Monday through Thursday at 3pm at Central, West, & South Junior Highs. For more info, go to wwwku.edu/~mmentors or e-mail us at mmentors@ku.edu
Music Mentors (CCO Program)
Center for Community Outreach challenging. educating empowering.
PAID FOR BY KU
November 10,2005
CAAS (Concerned Active & Aware Students) will host an afternoon of
Writing Up a Storm!
writing, revelry & refreshments on Sunday to benefit survivors of recent Gulf Coast storms.
For more info, go to www.writing.ku.edu Writing Up a Storm will take place on Sunday @ 1 pm in the Hawk's Nest of the Kansas Union
Center for Community Outreach
outreach, educating, empowering
November 15th @ 7pm Hawks Nest @ Kansas Union
Is the Death Penalty Just?
Cosponsored by ACLU, KU Amnesty, and KU Students for Life
Student Senate has begun accepting applications for the following replacement senator positions:
- Graduate and Law Senator
- Freshman/Sophomore
CLAS Securities
- CLAS Senator
- Junior/Senior CLAS Senator
- Social Welfare Senator
Applications can be found in the Student Senate office in 410 Kansas Union and are due by 5:00 pm, Wed. November 9th.
If you have questions regarding your eligibility or the applications process, visit the website or contact
us by phone, 785-864-3710