Wednesday, February 9, 2000
The University Daily Kansan
Section A · Page 9
Free to a good home
Sarah Canfield, Kansas City, Mo., senior, plays ball with her dog, Chloe, and another dog near Potter Lake. Canfield found the dog Monday on campus and is looking for a home for it. Photo by Kara Traus/KANSAN
KU to study breast cancer
By Warisa Chulindra
writer@kansan.com
Kansan staff writer
The University of Kansas Medical Center and the Kansas Cancer Institute are recruiting postmenopausal women to participate in one of the largest breast cancer prevention studies ever undertaken in the United States.
The National Surgical Adjuvant Breast and Bowel Project are conducting the Study of Tamoxifen and Raloxifene — two medications that are supposed to help prevent breast cancer — at more than 400 hospitals and clinics nationwide and in Canada and Puerto Rico. The study will examine whether Raloxifene is as effective as Tamoxifen in reducing the occurrence of breast cancer in high-risk women.
If the study shows that Raloxifene is as effective as Tamoxifen, it could be used for women who experience side effects from Tamoxifen, which include blood clots in the lungs and an increased chance of a stroke.
Through physician referrals, mailings, education programs and press releases, the Med Center and the Kansas Cancer Institute have recruited 33 women, said Renea Studer, registered nurse and study coordinator at the Med Center and the Kansas Cancer Institute. The Med Center and the Kansas Cancer Institute are continuing to recruit women with the goal of having 600 participants by July 1, 2004, Studer said.
Participants will take two pills a day for five years. One pill will be Tamoxifen or Raloxifene, and the other will be a placebo. A doubleblinding process will be used so that neither the participant nor the doctor will know which pill is which.
Participants will receive mammograms, physical exams and gynecological exams on a regular basis.
After the women stop taking the pills, the effects of the medication will be followed for an additional two years. Clinical trials will follow, along with studies on the safety of Raloxifene on premenopausal women.
RISK FACTORS
Age. The risk for cancer increases as a woman ac
Number of first-degree relatives with breast cancer. When breast cancer has been diagnosed in a relative, a woman is at greater risk
Whether a woman had any children and age at first delivery. Not having children increases risk, and the older a woman is when her first child is born, the higher the risk.
The number of breast biopsies a woman has had. More breast biopsies increase the risk of cancer, especially if the tissue showed a condition known as atypical hyperplasia.
The woman's age of her first menstrual period. The younger a woman is, the greater the risk.
Source: The National Surgical Adjuvant Breast and Bowel Project and the National Cancer Institute.
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