University Daily Kansan
Thursday, February 22, 1973
3
Med Center Develops Cancer Test
By MYLA STARR Kansan Staff Writer
A new cancer detection method being investigated at the University of Kansas Medical Center could lead to earlier detection and treatment of breast cancer, according to doctors involved in the program.
The test, which is based on detection of an antibody that has been found in the blood of some cancer patients, has shown some encouraging results. Dr. William R. Jewell, assistant director of surgery at the Cancer Centre and researcher in the program, said recently.
"We have established that something happens," he said. "Now we are trying to prove that there is a serological response in cancer patients."
According to Dr. Loren J. Humphrey, chairman and professor of surgery at the Medical Center and co-developer of the program, two or three years may be required to determine the accuracy of the test.
"It's a numbers game," he said. "We will need to test many subjects."
Jewell said that the total number of blood samples tested would depend on the specificity of the reactions, but he estimated that between 600 and 800 samples would be
Humphrey said that blood samples from 140 women with breast lumps had been tested so far. The antibody was found in 30 per cent of the samples from women with breast cancer, he said, and in 12 per cent of the samples from women with fibrocystic
disease, a precancerous condition of the breast.
Only one of about 80 samples from patients with benign lumps or no breast cancer are tested.
Continuing research may help to determine why all of the women with breast disease did not have the antibody, Humphrey said. He said that if the antibody was present in some women as well as to other cancerous tissues, it might be a general reaction to malignancy.
ied
"We're trying to determine if the body reacts to just breast cancer, or to severe breast disease that is not cancer, or to other cancerous tumors." Jewell said.
According to Jewell, the research is the only project of its kind in the country, although other methods of cancer detection are being investigated.
He said that the test was similar to the Gold test, which is also based on serological response to cancerous tissue, but that the test used to test the blood were different.
Humphrey said that he began investigating serological response to cancer in 1967 while at the University of Kentucky. He became interested in the reaction while evaluating patients who had been treated with cancer vaccine, he said.
In 1968, Humphry_jy joined the Medical staff of Emory University in Atlanta and continued the research with the help of Dr. Robert Boehm, an immunologist who is also involved in the Medical Center research.
While at Emory, Boehm and Humphrey found the antibody they are studying and
Humphrey said that the test was based on immunotherapy, or the treatment of cancer by using a patient's natural immunity to suppress the immune system that have a built-in defense to cancer he said, and that persons who develop the disease are those whose natural immunities are weak.
began development of a specific blood test for cancer.
Two years ago, Boehm and Humphrey came to the Medical Center and began working on a program to obtain a large number of blood samples for testing in a lab. This year, they joined Humphrey at the University of Kentucky, later came to the Medical Center project
The program is funded by a five-year
funding from the National Cancer
Institute, devel and贤
The grant provides about $60,000 a year, and is used to pay for technicians, mailing costs of blood samples and computer time, he said.
Information from the patients doctors and laboratory data are being compiled by computer, he said, and the first printout was received two weeks ago.
Jewell said that he and Humphrey began talking to doctors throughout the state about a year and a half ago about sending blood samples from all breast disease cases. He said that 60 Kansas doctors were now participating in the program.
Jewell said that the main goal of the research was to test enough samples to determine the accuracy of the test in both cancer and non-cancer patients. Another
goal is to increase the sensitivity of the test so that it will be able to detect as many cancerous tumors as possible in an early state of development, he said.
Jewell said that a related project was the establishment of a breast disease detection center at the Medical Center.
The American Cancer Society and the National Cancer Institute hope to fund about 15 or 20 such centers across the nation, he said.
A proposal for a breast disease detection center at the Medical Center has been submitted by joint commission of the two medical groups, and a mid-summer decision is expected
Mammography, he said, is an established x-ray technique for breast tumor detection that has recently come into wide use. Thermography is an ultrasound technique that registers the heat generated by increased blood circulation around a tumor, he said.
Jewell said that a breast disease detection center at the Medical Center would administer physical examinations and use mammography to detect tumors such as mammography and thermography.
Jewell said that if a breast disease detection center was established at the Medical Center, a blood test for the antibody now being studied would be made on patients with results which would be compared with results from other tests administered at the center.
Ruling Eases . . .
(Continued from Page 1)
decrease and that the population of Johnson County was expected to increase.
He said the three-judge panel did not accept such projections and wanted all districts to be more equal by present population figures.
The Apportionment Committee of the House earlier Wednesday heard several county officials say it would be difficult to comply this year with a proposed change in the date that county population figures are to be reported to the state.
The reporting date for population figures is now July 15, but state officials said that last year some counties did not get their reports in until October.
The committee wants to speed up compilation of population figures so that 1973 populations can be used in drawing up a proposed apportionment for consideration in the 1974 legislative session ahead of the deadline.
The committee voted to introduce a bill calling for a May 15 deadline for population figures. George Schnellbacher, Shawne County County Judge, said by her testimony, the date to May 15 would make it possible to plan and meet this deadline in the future.
Counselors Sought
Campus Briefs
The Mid-Western Music and Art Camp is seeking counselors for its summer session. Room and board and a $50 stipend will be provided for the eight-week camp. Seniors and graduate students are preferred, although others will be considered. For an interview appointment, contact Russell Wiley, professor of music.
Costa Rican Study
The Philosophy Club will meet 7 onight in the Curry Room of the Kansas Union. Joe Van Zandt will speak on "Kant and Freedom."
The Foreign Study Office said Wednesday that 16 students from various parts of the country had arrived at KU for a two-week course in French. Students will be Costa Rica for an 10-month Study Abroad Program. One of the lectures, entitled "Everything You Wanted to Ask About French," will be given by Jon Vincent, assistant professor of Spanish and Portuguese at KU.
Philosophy Meeting
Justice William Reinhquist of the Supreme Court said for the majority that even in 1964 when the court first applied to the "one-man, one-vote" standard to state legislative districts it allowed great flexibility from a court in drawing U.S. congressional lines.
Writers Award
Entries are now being accepted for the Fourth Education Writers Award, sponsored by the American Association of University Professors. Examples of entries will be made in both the print and broadcast media between March 1, 1972, and March 1, 1973, are eligible. Announcement of the award will be made at the association's annual meeting April 27 in St. Louis. Entries should be submitted to the information officer, Suite 500, One Dupont Circle, Washington D.C. 20036. Deadline for entries is March 5, 1973.
He said, "Application of the absolute equality test of the court's rulings in congressional cases to state legislative bodies is not correct," fioning of state and local governments."
The Sailing Club will meet 7:30 tonight in the Kansas Union. All members as well as those interested in joining are welcome to attend.
Sailing Club Tonight
But Justice William J. Breman Jr., dissented, and said the court had never held that different constitutional standards were not equal to those of U.S. concessional resoultionism.
"The need to preserve the integrity of political subdivisions as political subdivisions may in some instances justify small variations in the population of districts from which state legislators are elected," he wrote.
"But that interest can hardly be asserted in justification of 'malapportioned consent.'"
League of Women Voters To Hold Finance Meetings
The Planning and Zoning Committee of the League of Women Voters will hold unit meetings Thursday and Monday to obtain a consensus on the financing of city improvements, according to Claudette Smith, publicity chairman.
Questions to be considered will be whether Lawrence should change its policy of public financing of internal improvements, whether Lawrence should adopt a capital improvements master plan and whether expenditure of public monies should be shifted from financing improvements to paying present expenses.
The committee has studied city loans for capital improvements, bond and interest levies, the effect of delinquent assessment taxes and benefit district financing and its alternatives in preparation for reaching a consensus.
Ave. at 1 p.m. in the home of Mrs. Milo Stucky, 508 Pioneer Ridge and at 8 p.m. in the home of Mrs. Richard Moore, 715 Lawrence Ave.
Mettings will be held at 9 a.m. Thursday in the home of Mrs. Clark Coan, 1646 Barken
The Monday meeting will be held at 9:15 am. in the First Christian Church.
Committee to Discuss Graduation Reunion
The Gold Medal Club consists of alumni whose classes have held their 50 year reunions. This year the club includes all classes up to and including the class of 1922.
The planning committee of the Alumni
Old Medal Club will meet today to discuss
the program.
Last year, about 125 club members attended activities at commencement, according to Steve Clark, assistant director of the Alumni Association.
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