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Discovery in KU lab may help cancer patients
KATHERINE HARTLEY
@kat_hart9
University Pharmacy Professor Jennifer Laurence and her team of undergraduate and graduate students have been working for the past nine years on an accidental discovery they made that could potentially help lessen the harsh side effects of cancer treatments.
"This project was sort of a fortuitous accident when it began," Laurence said. "We were working on trying to study a protein to understand its role in cancer, and in making that molecule and trying to analyze it, we discovered that something would shut it off after we made it. So in trying to figure out how to do that research project, we actually had to solve this other problem, and that became the basis for this very new innovation."
The innovation itself is a piece of protein that is three amino acids long and has the unique capability of binding to metals.
That small piece of protein also binds to other metals, which can be helpful in imaging, an approach to lighting up tumors.
When it comes to treating cancer, metals are very useful and therapeutic. Platinum is used in a number of drugs to treat cancer, and the goal of Laurence's lab was to use their discovery to deliver that platinum directly to the cancer cells.
"Doctors can see what's happening to the patient, what their disease state is and how they may be responding to therapy, regardless of what type," Laurence said. "We can use that with imaging metals in order to light up tumors and to detect them and determine if there's a change."
The new innovation will target tumors and cancer tissues directly and separately instead of also killing healthy tissue, which is how chemotherapy now works. This prevents the terrible side effects of the treatment.
Laurence's team consists of undergraduate, graduate and post-doctoral students who do the research part, while her biotechnology company, Echogen, helps with the funding and patent part of the process. Echogen will also be the team that creates a real product that can be taken to clinics and used on patients.
"This is what we would call personalized medicine," Laurence said. "So you're heading towards the goal of treating a patient effectively with a much more gentle approach to give them a better quality of life and a better experience as a patient."
"Echogen is responsible for trying to commercialize this," Laurence said. "So taking the base discovery from the University of Kansas, Echogen licensed the patents that are filed and is pursuing lead products to be able to take these into the clinic and have an impact on patients. So the progression is a team of people here at the University of Kansas that were involved in the discovery and the early stage research to support knowing that this had value and then the company's role is to actually take that to make products and move forward." Last Thursday, Laurence's discovery was featured on "Cancer in KC," a special that aired on KCPT and demonstrated the current goings-on, innovations and new discoveries in the region's cancer research field.
Edited by Callie Byrnes
WATKINS FROM PAGE 1
choice of enrolling each semester or annually.
For those studying abroad or planning on traveling, the new plan will continue to provide health insurance while off campus, even though the amount of on-campus services provided at Watkins is higher.
"Students have to pay for the medical care at the time of service, but should keep their invoices or claim forms, and submit them to [UnitedHealthcare] when they are back in country," Malott said. "If it is a covered service,
Although the benefits offered by Watkins are similar to past years', the additional benefits required by the ACA can help students in need of cost-effective health care. Watkins makes sure it provides the level of benefits mandated by the ACA so the plan offers additional protection for students.
If interested in signing up for the new health care plan, more information is available at Watkins or on its website at studenthealth.ku.edu.
[UnitedHealthcare] will reimburse the student."
Edited by Mitch Raznick
DOMINICK REUTER/ASSOCIATED PRESS
Former NFL star tight end Aaron Hernandez convicted of murder in shooting, sentenced to life
Ursula Ward, mother of the victim, Odin Lloyd, speaks to the media after former New England Patriots football player Aaron Hernandez was convicted in his murder trial at the Bristol County Superior Court in Fall River, Mass.
FALL RIVER, Mass. — Former New England Patriots star Aaron Hernandez was convicted of first-degree murder and sentenced to life in prison Wednesday for a deadly late-night shooting, sealing the downfall of an athlete who once had a $40 million contract and a standout career ahead of him.
Hernandez, 25, who had been considered one of the top tight ends in professional football, shook his head, pursed his lips and sat down after the jury forewoman pronounced him guilty in the slaying of Odin Lloyd, a 27-year-old landscaper and amateur weekend football player who was dating the sister of Hernandez's fiancee.
his fiancée, Shayanna Jenkins, cried and gasped when they heard the verdict. Hernandez, his eyes red, mouthed to them. "Be strong. Be strong." Lloyd's mother also cried.
Hernandez's mother, Terri, and
Jurors deliberated for 36 hours over seven days before rendering their decision, which also included
convictions on weapons charges.
convictions on weapons charges." The jury found that he was just a man who committed a brutal murder," District Attorney Thomas Quinn said after the verdict. "The fact that he was a professional athlete meant nothing in the end."
Associated Press
SENATE FROM PAGE 1
The bill would limit the opportunity of students to diversify, Gewirtz said.
"College is an opportunity to branch out, and part of that is learning about other religions and other cultures," he said. "Being restricted would not be a good feeling."
Fitzgerald said he doesn't understand where the discrimination argument is coming from.
"Discrimination has gotten a bad name as a word, but it's not necessarily bad," he said. "Fraternities and sororites have their ideals and they absolutely have always had people not allowed in their fraternity or sorority because of bad behavior or because they no longer adhere to those ideals. That's never a problem, and now this becomes a problem. I'm not sure I understand"
Although Fittgerald sees this as a non-issue, Gewirtz said this is blatant discrimination.
"This is eliminating other groups of people from a group, and it discriminates against all groups that may not have ties to the religion or what the club is," Gewirtz said.
Last year, the Kansas Senate killed a discriminatory sexual orientation bill, and Haley said he hopes the House will mimic that action of stopping discriminatory bills. If the House doesn't succeed and it is passed into law, Haley said he wouldn't be surprised to see this challenged in court.
"Perhaps the House will return the favor and kill this bill," he said. "This could be a subject of the First Amendment right to affiliate. So, if this goes to court, I don't see how it could be upheld. What benefit does it serve to exclude someone?"
Edited by Mackenzie Clark
DINING FROM PAGE 1
one of the main reasons customers see the regular price increases.
we've managed to keep our [residential] increases each year for the past three or four years under 3 percent, so that's something we are very proud of." Golledge said.
She said the increase has been approved by the Student Housing Advisory Board, the chancellor and the Board of Regents. That rate increase will be 2.9 percent, and the retail rate increases will be about the same: 2 to 3 per cent.
Golledge also said the department plans to raise its minimum wage for part-time student hourly workers from $7.80 per hour to $9.22 per hour in anticipation of a federal minimum wage increase There are also environmental factors.
Dining Services gets some of its goods from local sources in Kansas, where the vast majority of the state is under a degree of drought condition, according to the University of Nebraska-Lincoln's Drought Monitor.
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"We try to keep our prices as affordable as possible for our Jayhawk families," she said.
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Golledge said the price increases do their job of covering increasing costs each year.
The University currently charges $15 more for a top residential meal plan than Kansas State University and $44 more than the University of Missouri, but $686 less than Nebraska, which sits at about $4,250 for an equivalent plan, according to KU Dining. These numbers do not include retail value like the University's "Cuisine Cash."
"We have a chef that makes it for us, so we don't have as many options as if I were to eat on campus all the time. But I guess if you break down the cost of it, it's a little more cost-effective to eat there," Yungmeyer said. "Two dollars for a drink; it seems a little expensive."
Some students said they believe the convenience of dining on campus is offered at too high of a price.
"If this continues, I probably won't [eat Dining meals], because as a college student I'm broke, and I don't have money to spend on those foods," said Steve Kim, a sophomore from Overland Park. "It's overpriced for sure."
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"The droughts will play into the increase in the food flow for next year," Golledge said. "California plays a big role in that with some of our produce, so we'll factor that in."
Leawood sophomore Annie Yungmeyer said she prefers to eat at the Delta Delta Delta sorority house for convenience.
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