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University Daily Kansan
Wednesday, Dec. 5, 1962
Staphylococci Replace H-Bombs Quite Nicely
By Delos Smith UPI Science Editor
NEW YORK-The news from the bacterial world is good for bacteria but threatening for people. It is this; bacteria have advanced one more step toward a conquest of the antibiotics which once stopped them cold.
Some strains of these disease-causing microorganisms have learned how to "resist" antibiotics — and some strains have even become dependent upon antibiotics for survival and growth.
"Alice in Wonderland," KU's first Children's Theatre production of the season, will open at 4:30 tomorrow afternoon in the University Theatre.
Performances will be at 4:30 and 7:30 p.m. Friday and Saturday.
Alice in Wonderland Opens Tomorrow
The play ran for five performances in Kansas City last week.
G. Baley Price, professor and chairman of the mathematics department, will speak in a symposium at a National Science Foundation meeting Friday and Saturday in Chicago.
KU's seventh summer institute for high school and college teachers of mathematics June 10-Aug.3 under a National Science Foundation grant of $97,700.
After 18 more transfers to broths containing larger and larger quantities of neamine, the bacteria were fully "resistant" to neamine, that is, they multiplied despite its presence in high concentrations.
The NFS meeting is being held to orient directors of summer institutes for college teachers of mathematics. Prof. Price will direct
Professor to Attend NSF Meet in Chicago
SOME EVEN HAVE learned how to switch this dependency from one antibiotic to another. This raises the possibility of a day coming when it will be more life-saving not to put an antibiotic into a sick person than to use one.
The chemists kept right on transferring the bacteria to neamine-richer broths and after 20 more transfers they had a strain of staphylococcus aureus which couldn't multiply unless it had neamine in its nutrition.
PATRONIZE YOUR
For some time, and in scattered places, bacteriologists have been coming upon bacterial strains which couldn't survive unless they had access to streptomyein, one of the first and most effective antibiotics.
Democracy is the theory that the common people know what they want, and deserve to get it good and hard.—H. L. Mencken
In an effort to get to the bottom of this phenomenon, three chemists used staphylococcus aureus, a bacterium which causes many human illnesses. They cultured these "bugs" in a nutritional broth containing a tiny bit of the basic antibiotic, neamine.
FOR THESE BACTERIAL strains, streptomycin has stopped being a death-dealing agent and has become a necessity for life.
THERE WASN'T ENOUGH of neamine to prevent them from multiplying—just enough to give them experience with it. When transferred to a broth containing a larger amount of neamine, they kept on multiplying.
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In each case, the chemists said, "the organism utilized the antibiotic for its neamei requirement."
(All are basic antibiotics and are chemically related to one another and to neamine.)
The bacteria, however, were unable to substitute four other antibiotics for neamine and this ended their growth. But this provided no simple explanation because these four have chemical affinities with the four the bacteria could use.
THE CHEMISTS ALSO had contradictory experiences with strains of the common bacteria, escherichia coli, mycobacterium, and sal-monella paratyphi which had become dependent upon streptomycin.
The scientific answers for these people-threatening events in the bacterial world are not yet in hand.
The chemists were W. T. Sokolski, R. L. Yeager and G. C. Chidester of the control laboratories of the Upjohn Company, Kalamazoo, Mich.
I should fancy that the real tragedy of the poor is that they can afford nothing but self-denial.—Oscar Wilde
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available at ALLEN'S Drive-In with $1.00 purchase.
See this outstanding show FREE Saturday, December 8, at the VARSITY THEATER at 11:00 p.m. only.
The Drive-In which is interested in YOU, the Students of KU
1404 W 23rd