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DEPARTMENT OF HEALTH EDUCATION KU labs work with health projects Emphysema, substance tracers part of Oread, Higuchi's work Diane Thompson, Oread Laboratories senior scientist, works with Carl Kindberg, senior scientist Kent Gilbert/KANBAN By Travis Butler Kansan staff writer A researcher at the Center for Bioanalytical Research at the Higuchi centers is working with Oread to develop a method for testing the effectiveness of emphysema drugs, said Osborne S. Wong, technical manager for Oread. Also, Richard Givens, chairman of KU's department of chemistry, is working on new analytic methods for detecting trace amounts of many biological substances. Two recent research projects highlight the close connection between Oread Laboratories and KU's Higuchi Biosciences Centers. "We were approached by a person at a pharmaceutical company that wanted to develop a substance to regulate elastase," Wong said. Elasat is an enzyme that breaks down lung tissue in the course of the disease. Susan Lunte, a researcher at the Center for Bioanalytical Research, is working on a way of testing the effectiveness of emphysema drugs, she said. She is measuring a by-product of the lung degradation caused by the disease, which allows testers to monitor the effectiveness of the treatment. Oread's other KU project is being "We're using it as a method to detect trace amounts of analytes," he said. "Analytes are what you're looking for in the analysis. It could be amino acids, peptides or any of a whole number of biological substances that we want to detect in low concentrations." done with the chemistry department, Wong said. Researchers are working on a way to use chemiluminescence to improve analytical methods. Both research centers were established by the late Takeru Higuchi, a Regents distinguished professor of chemistry and pharmacy at the University of Kansas. "Oread scientists work with our scientists to turn basic research findings and instrumentation designs into products and services," said Shirley Domer, director for resource development at the Higuchi centers. "Oread was formed for this very purpose. The two organizations were designed to work together." Charles Decdeu, executive director of the centers, said Oread was the primary corporate sponsor for the Center for Bioanalytical Research. When the center was incorporated into the Higuchi centers, Oread came with it. It has become the principal corporate sponsor for the centers. "We have a related sort of interest," he said. "They're the first Wong said, "We usually get our ideas through our professional contacts, through publicity we have, referrals from our colleagues in industry or from some of our collaborators at the University." people we go to when we think we have commercial ideas within their purrview." "They're still a very strong link to the financial world," he said. "We get ideas for projects of corporate enterprise for very willing and very cooperative." Decedue said Oread provided a corporate connection for the centers. Oread researchers work fairly closely with KU researchers, Wong said. The amount of contact varies, on the stage of the research. Then Oread brings in a time frame and cost projection for the project, he said. If the results are favorable, Oread does the project. "It would depend on the expertise and capabilities we have in that area or whether we even have access to the capabilities needed." Wong said. Decedue said, "We do the research, and they do the development." Listen to Mother Nature. Weather Map THE UNIVERSITY DAILY KANSAN Imagine. Imagine a state law that forces pregnant teenagers to tell their parents if they want an abortion, even in families plagued by physical violence and sexual abuse. Imagine a state law that drives pregnant teenagers away from safe, confidential medical care. Imagine a state law that makes abortion impossible for many pregnant girls and forces them into teenage motherhood. imagine a state law that devastates the future of young women by stunting their education and career opportunities. Stop imagining. These laws are real. The American Civil Liberties Union fights laws that violate a teenager's right to privacy and equality — laws that violate a teenager's right to choose between childbirth and abortion. Imagine the difference we can make with your help. Write us. ACUW Reproduction Forms Request, 120 West Washington Street, New York, NY 10024 --- ACLU Reproductive Freedom Project, 132 West 43rd Street, New York, NY 10036