8
Thursday, February 1, 1979
University Daily Kansan
Rats get no-knock gas treatment
A KU professor is studying the effect on rats of MMT, an anti-knock agent in unleaded gasoline, to determine how the chemical damages lung tissue.
Robert P. Hanzlik, associate professor of medicinal chemistry, said he did not think MMT, methylcyclopentadienyl manganese tricarbonyl, posed a threat to humans. However, he said MMT could be fatal to rats and warranted investigation.
Hanzilk said MMT was not toxic when burned but caused lung damage and death in rats when administered unburned orally or by injection.
"We're going to start exposing rats to an atmosphere with small concentrations of MMT to test how inhalation of it affects them," he said.
HANZLK SAID MMT was an only substance that travels through the bloodstream to areas of the body rich in lipids, or fats.
In the lungs, MMT passes through the cell walls, which are partly composed of lipids, into the cells. Hardik said he was not fully aware that MMT affected the cell after it got inside.
"There is essentially zero exposure to MRT for humans through gasoline," he said. "I don't think there is a human source of pollution all over the country. But it is unknown."
He said that the term "toxic," as it applied to chemicals, was a relative term.
"MMT IS QUITE toxic compared to most things you would call toxic. A lethal dose for a rate is 10 to 15 milligrams. It would be about three and one-half grams of MMT for a 150-pound person," Hanzlik said.
He said it would take 20 gallons of gaseous water to make three and one-mill grams of methane.
"We want to find out how lungs as tissue react to toxins, and whether there are any common features among the breakdown mechanisms in these toxins," he said.
MMT is one of several lung toxins Hazlilik is studying.
"MOST ANIMAL systems react to a foreign compound by transforming it into compounds that can be readily excreted," he said.
Hanzik让 a substance could be toxic in its original form or it could be metabolized by the body into compounds that are toxic.
He said the biological mechanisms that break down substances into compounds that can be excreted are similar in animals.
"Most of our evidence indicates that MMT itself is very toxic, and not its metabolites are more toxic."
biotransformation for it to be toxic," he said.
Hanzlik said that a chemical usually underwent extensive toxicity testing before it was allowed on the market, but that MMT had not been tested thoroughly.
Hanlikzil has his studies might provide a basis for designing measures to save persons who ingest a toxic dose of chemicals.
MMT WAS FIRST used as an additive to
baby years ago in specialized fuels.
About five years ago it was used to replace
tetraethyl lead in regular gasoline.
After that, fuel became more important
when it is burned by car engines. It also
is a toxic in unburned state.
Hamikil said he thought MMT would be phased out of the market because its hybrids diminished the effectiveness of catalytic converters.
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Del Shankel, executive vice chancellor,
was quizzed yesterday by members of the
University Senate Executive Committee at
its regular meeting.
SenEx questions Shankel; criticizes search group
Shankel, attending the committee meeting for a monthly briefing, answered questions about his selection of the search agenda and his new vice chancellor for academic affairs.
Members of SenEx complained that Shankel, in his selection of the members of the search committee, bypassed many of the candidates SenEx recommended. SenEx drafted a resolution last month criticizing Shankel's role in the selection.
Shankel last month selected a 12-member search committee to interview candidates for the position, now held by Ron Calgaard. Calgaard is scheduled to become president of Trinity University in San Antonio, Texas, July 1.
F. Hutton Barron, professor of business and a member of SenEx, said he wanted to make sure Shankel realized what the resolution meant.
"We're not questioning your authority," Barron said. "But it seems you limited
SenEx to a token role. It seems appropriate you would meet with us to ask for permission.
Shankel said the pay raises did not need to be included on the priority list because the list dealt primarily with building projects and program funding.
Shankel the legislators had asked the administration to prepare a list of the University's top 10 or 12 priorities. SenEx members asked Shankel to include the proposed 7 percent faculty pay raise as one of the top priorities.
Sarm Swiefeil, SenEx graduate student representative, complained to Shankel about the lack of graduate students on the selection committee. In response, Shankel to review with him the position of four finalists for the position.
In other business, Shankel told the committee about the inspection tour made by a Kansas House Ways and Means subcommittee yesterday. The subcommittee was on campus to discuss the University's budget requests with KU administrators.
A call for a quorum and a subsequent move for adjournment prevented several items on the agenda of last night's Student Senate meeting from reaching the floor. Because of one resolution not on the agenda we angered at the early close of discussion.
Senators quit early agenda left unfinished
The resolution, in support of the Integrated Humanities Program, was submitted yesterday by Robert Green, Hays senior, and Craig Templeton, Topeka junior. Green had hoped to et the resolution on the agenda before adjournment.
Green, who has never been involved in IHP, said he supported the resolution as a specific stand on freedom of speech by the Senate.
"TIM NOT saying that I'm for IPH"
He said. "I'm for the right of IPH to
be said."
Green described the Senate's quick adjournment as typical.
Staff Reporter
"A lot of people talk about freedom of speech but not too many are really interested when it comes to specifics," he said.
The resolution said, "A spokesman for the program defended it in clear and ringing English, an oppo- tion to the governor's standing from Strong Hall, for the purpose of preventing the slow strangulation of the IHP. . . Therefore be it resolved that the governor's Kansas strongly support."
Green said he was disappointed by a lack of support from graduate students.
GREEN SAID supporters of IHP had
and had recieved from the Senate last spring
and had received
"Some of the graduate students should
be "he" said. "Many of them were
at the free summer camp."
Green's resolution criticized opponents of IHP for being vague in their opposition and praised Dennis Quinn, IHP director, for his defense of the program.
By CAROL BEIER Staff Representer
The Senate also passed one resolution and two bills, in addition to hearing guest speaker Wallace Greene on "Inflation and the Student."
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"The President's program is balanced and even-handed," Greene said. "It sets up standards for business and labor but recognizes that the federal government must take the lead in recognizing its past mistakes.
Rent and utility rate increases are also
controlled. President's voluntary
controls Gyeongbu.
Greene said that the wage and price guidelines apply to schools and that increases in tuition and fees, when averaged on board and should be in compliance.
and price guidelines, as outlined in a Wage and Price documentation of the Council on Wage and Price Standards.
Lambda Sigma Society
A sophomore coed honor society at the University of Kansas in now accepting applications from the mathematics department may pick up an application form from his living room, the Office of Student Organization.
Applications due Feb. 20
"BUSINESS, LABOR and government have contributed to the problem of inflation and all three must contribute to the solution."
If you have any questions, please inquire at the Office of Student Organizations and Ac tivities.
Students with specific questions concerning the President's proposed budget and wage and price guidelines should have access to this information on Wage and Price Stability, Greene said.
Questions may be mailed to Stuart Schmid, Council on Wage and Price Stability,
728 Jackson PL, NW, Washington D.C., 20506.
20506.
JAZZ
TONIGHT: KU HONORS STUDENTS ASSOCIATION will meet at 7 in the Big Eight Room of the Union. STUDY SKILLS ENRICHMENT WORKSHOP will be at 7 in the Union parrons. KU SKYDIVING CLUB will meet at 8 in Room 140 of Robinson SHIRT COMPANY will be at 8 in Parron C of the Union. THE YOUNG SOCIALIST ALLIANCE will give a class on socialism at 7:30 in the Oread Room of the Union.
TOMORROW: OPEN HEARINGS ON GOVERNANCE IN THE SCHOOL OF SOCIAL WELFARE will be held from 3 p.m. to 5 p.m. in the Walnut Room of the Union. SOVIET AND NEW YORK UNION POLITICAL SCIENCE LECTURE—Robert Sharlet of University College in Schenectady, N.Y., and Armensity International will speak on "Patterns of Repression in East Europe and the U.S.S.R.: The Forgotten Dissidents" at 7:30 p.m. in the Forum Room. He will meet at 7:30 p.m. in Room 173 of Robinson Gymnasium. There will be a free dance at Templin Hall starting at 8.
JAZZ
TODAY: BFSC FORUM, "Manipulation of the Media for Economic and Social Forces" by Samuel Adams, School of Journalism, will be from 3 p.m. to 5 p.m. in New York. Students will study STUDY ABROAD for applying to study in Great Britain. More information may be obtained from the Office of Study Abroad, 108 strong, OPEN HEARINGS on Wednesday, June 27, at 9 a.m. OF SOCIAL WELFARE will be held from 3 p.m. to 5 p.m. in the Walnut Room of the Union.
IN OTHER business, the Senate approved a resolution in support of the establishment of an International Student Center. Mark Bernstein, Lawrence graduate student and sponsor of the resolution, said the center would house offices for international student organizations and a library of international publications.
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The Senate also passed a bill to use $6,138 from its internal unallocated reserves to resurface 10 tennis courts, 8 behind Robinson Gymnasium and 2 near Memorial Stadium. According to Make Harper, the college will offer training for the project will come from the Department of Health, Physical Education and Recreation Services.
After a lengthy discussion, the Senate approved $909.14 in supplemental funding from the Senate's unallocated account for the University Dance Company.
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