THE FAR SIDE
5
By GARY LARSON
The committee to decide whether spawning should be taught in school.
State/Local
States decide date for waste site vote
LITTLE ROCK — Kansans may find out in November whether a radioactive waste disposal site will be built in their state.
The Associated Press
The Central Interstate Low-Level Radioactive Waste Compact State, a group of states being considered for the site, instructed a consulting company to continue the process for selecting the host state despite objections from Nebraska.
The commission later set Nov. 16 as the date for the commission vote on the host state recommendation. That meeting was tentatively set for New Orleans, Jim Peery of Atlanta, Ga., the commission's executive director, called it the ultimate meeting.
Alluding to each state's general lack of desire to have the site, Peery noted that the date was near Thanksgiving and told the commissioners, "Perhaps some of you may be giving more thanks than others."
Four of the states in the compact, Arkansas, Kansas, Louisiana and Oklahoma, owned a tween or U.S. Ecology of Louisville, Ky., to go ahead with a
selection process "which shall be rational, systematic and verifiable," and which "shall treat member states fairly and equitably."
The motion spelled out selection criteria, but the Nebraska representative objected to whether the criteria should include credit for states that provide waste-management services for hazardous wastes. Grams said there were no disposal sites in Nebraska for hazardous waste. The other states have some hazardous-waste disposal sites.
But later in the meeting, Nebraska was able to get the other commissioners to go along with specific limits on the waste that would be considered for credit. But Nebraska could not get the commission to accept a proposal to allow each state to count a disposal site that may not be operated by an agency, but but be operating by Jan 1, 1993. If a firm's application is on file by Nov. 1 of this year, though, it could be counted, the commission decided.
The criteria, according to the motion, shall include factors related to groundwater and geologic formations.
Drug may safely reduce cholesterol
By AMBER STENGER
Staff writer
Dorothy Thomas said that she had been fighting high cholesterol for 17 years. Now she may have found a treatment that reduces her cholesterol level and does not cause side effects.
Before using lovastatin, a drug recently approved by the Food and Drug Administration, Thomas, Lawrence resident, had tried dieting, exercising and several drugs to fight cholesterol. Those drug treatments created intestinal and stomach problems for her, she said. So far, she has not had any side effects from lovastatin.
Thomas said that she had been receiving cholesterol treatment from the University of Kansas Medical Center for more than 10 years. She has been using lovastatin for two years.
During that two-year period, her cholesterol level has decreased from 351 milligrams for every 100 milliliters of blood to 238 milligrams, she said. The optimal level is 200 milligrams.
University Daily Kansan / Wednesday, September 23, 1987
The Med Center is one of 12 hospitals in the nation conducting tests on lovastatin. The Med Center's Lipid and Arteriosclerosis Prevention Clinic has been testing lovastatin for three years. Forty volunteers, including Thomas, are being treated with the drug at the clinic.
Carlos Dujovne, director of the Lipid Clinic, said that he was optimistic about the drug because it was effective and convenient. But he said the question now is whether the drug is safe to take over a long period of time.
Lovastatin is taken in pill form. Patients take two pills each day. The drug is marketed by Merck & Co. of New Jersey under the name Mevacor.
Cholesterol is one of the main contributors to heart disease, the nation's No. 1 killer. Foods that are high in saturated fat, such as egg yolks, beef and butter fat, contain high levels of cholesterol.
When too much cholesterol is in the body, it accumulates on the walls of the arteries. Buildup of cholesterol on arterial walls causes blood to clot.
"Cholesterol builds up because it does not belong in the body in excessive amounts," Dujonev said. He said that some people naturally produced more cholesterol than their bodies needed.
which can lead to heart attacks.
Recent studies indicate that when people consume too much cholesterol, their bodies also produce higher levels of cholesterol. HMG COA reductase, an enzyme in the liver that breaks down the amount of cholesterol that enters the liver regulates the amount of cholesterol that reductase manufactures.
He said special gates in the liver cell controlled how much cholesterol ester.
"The amount of a substance produced is regulated by the amount of substance in the environment." Dujoven said. "And so when there is cholesterol coming in, then this enzyme production is reduced."
"When there is a lot of cholesterol outside the cell, the cell reads that as having too much cholesterol," Dujovne said. "To protect itself, it shuts off the gates. When it shuts off the gates,
there is no cholesterol coming in. Reductase sees there is no cholesterol coming in, so it starts making more cholesterol."
Lovastatin works by inhibiting the response of the reductase, and thus reduces reductase cholesterol production, he said. The gates open again and normal cholesterol levels are restored.
Dujovine said that the drug had not caused any major side effects.
Because the patients at the clinic are volunteering for the tests, they do not have to pay for their treatments, which can cost from $1,000 to $5,000.
Thomas said that she volunteered because she believed that she had nothing to lose and because the staff at the clinic was thorough.
Clinic workers begin the treatments by encouraging patients to follow a low cholesterol diet, exercise regularly, stop smoking and reduce their weight. Dujove said. Drug treatment follows if cholesterol levels remain high.
Director: George Cukor.
Some of the best casting in
the history of film! Katharine
Hepburn is the spied
heiress; Cary Grant is
debronaion ex-husband;
and Oscar-winning Jimmy
Stewart is a cynical reporter.
All learn lessons in love, humility
and respect in this hysterical classic comedy.
(1940, 112 min/BW)
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