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University Daily Kansan / Thursday, October 3, 1991
Britain bans popular sleeping pill linked to dangerous side effects
The Associated Press
LONDON — The British government yesterday banned the popular sleeping pill Halcion and all other medicines containing the drug triazolam because of what it deemed potentially dangerous side effects.
Halcion is one of the most widely prescribed sleep medications in the world. Since it was approved in 1983 for use in the United States, more than 43 million Halcion prescriptions have been written.
In murder cases in Missouri and Texas, defendants have claimed they were under the influence of the drug. Halcion use was adopted successfully as a defense by a woman accused of killing her mother in Utah.
"It is now considered that the risks of treatment with triazolam outweigh the benefits," the department said in a statement.
The British Department of Health said medicines containing triazolam were associated with a much higher risk of haematopathic side effects particularly job-related.
Upjohn, the Kalamazoo, Mich. based makers of Halcon, failed to win an injunction Tuesday preventing the sale of the company. The company said it would appeal.
"There is absolutely no scientific or medical evidence that warrants withdrawal of Halcion tablets in the U.K. or
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The department said 1.5 million prescriptions for the drug were issued each year in Britain and Northern Ireland.
Triazolam is only available by prescription in the United Kingdom and is used for treating insomnia, the British Department of Health said.
any other country," said Dr. Theodore Cooper, Upjohn's chairperson.
In Salt Lake City, a federal judge is considering requests from people charged in slayings in Missouri and other states that involved purported side effects of Halcion.
Side effects associated with Halcion and other sleep medications range from drowsiness and dizziness to anxiety, insomnia and hallucinations.
The department urged triazolam users to consult their doctors before going off the drug because of the possibility of withdrawal symptoms, including insomnia and anxiety.
U. S. District Court Judge J. Thomas Greene said he soon would rule on requests to open the files in the suit of a former Utah woman, Ilo Grundberg, who claimed she killed her 83-year-old mother while using Halcon.
The Department of Health said its Committee on the Safety of Medicines recommended the ban after receiving 161 psychiatric reactions, including 161 psychiatric reactions.
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A murder charge against Grund-
Halcion vs. Restoril
Ratio of complaints reported by consumers using Halicon compared to similar complaints for the sedative Restoril:
Category Halcion Restoril
• Amnesia 46 : 1
• Agitation, anxiety or nervousness 9 : 1
• Psychosis, hallucinations, paranoia 16 : 1
• Confusion or delirium 14 : 1
• Hostility or intentional injury 19 : 1
• Seizures 37 : 1
SOURCE, Boston Globe, Food and Drug Administration Office of Epidemiology and Biostatistics
Grundberg and Upjohn reached an out-of-court settlement in August that included keeping secret thousands of pages of documents, including reports of violent and bizarre behavior associated with Halcion.
berg was dismissed after court-appointed psychiatrists testified that the June 1988 killing in Hurricane, Utah, was caused by her intoxication by the drug.
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