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University Daily Kansan
Friday, March 23, 1962
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A. Clos to Be Next Speaker In Humanities Lecture Series
"Is Tragedy Still Possible on the Twentieth Century Stage?" This is the question which will be answered in a Humanities Series lecture by a visiting British scholar Tuesday at KU.
The speaker will be A. Closs, head of the German department at the University, Bristol, England. He will lecture at 8 p.m. in Fraser theater and the Faculty Club will have an informal reception afterward.
During his four-day visit to the KU campus, Mr. Closs will also speak to classes in German literature, humanities, and drama, and will confer with faculty members and graduate students.
ON HIS AMERICAN TOUR, he will lecture at California, Princeton,
PHOENIX, Ariz. — (UPI) The scientific pioneer who has maintained unwavering faith in one of the most terrifying chemicals ever devised by man, believes he has been fully justified by events.
New Anti-Cancer Drug Is Potent In Early Tests
Three persons who over four years ago were at death's door because of cancer are not only alive but functioning. There are 91 more who by the usually unchangeable law of advanced cancer should have been dead for as long as three years.
DR. FRED J. ANSFIELD conceded these 93 are paying a stiff price in monthly installments for life. Monthly they must have a sickening treatment with this poisonous chemical. This is to renew the poisoning of cancer cells which originally spared them from dying.
These survival statistics are his vindication, Ansfield feels, even though the 93 are the survivors from over 1,100 terminal cancer patients whom Ansfield and his associates at the Cancer Research Hospital of the University of Wisconsin, Madison, have treated with the prime cell-poisoner, 5-fluorouacil — or 5-FU for short.
To have any chance of being effective, the drug must be administered in doses so large it poisons the whole body as well as the cancerous cells, Ansfield said in addressing the annual science writers' seminar of the American Cancer Society.
OF HIS MORE than 1,100 patients, 21 were actually killed by the drug rather than by their cancers, he said.
On the other hand, surgery and radiation had failed to help any of the 1,000 and more. Nothing more could be done for them except this chemical of desperation—5-FU.
For the past two years Ansfield has been using a relative of 5-FU, 5F-LUORO-2' — deoxyuridine — 5-FUDR — and with it has had some patients who developed no poisoning of normal cells whatever. This is "a circumstance which was never observed with 5-FU," he said. But some patients can't "tolerate" 5-FUDR at all.
BOTH DRUGS INTERFERE with the cancer cell's manufacture of its nucleic acids which contain the recipe for the making of more cells like itself. All normal cells also make their own specific nucleic acids, and the drugs interfere with them, too. So far it has proved impossible to poison the cancer cells without poisoning normal cells, although to a lesser extent.
Both 5-FU and 5-FUDR are difficult to make and expensive. A course of treatment with 5-FU costs about $40, which means $40 a month. With 5-FUDR the monthly cost is $200.
Ansfield said the prolongation of life is worth what it costs in the periodic sickness of the patients, in the difficult labors of administering physicians and in money. The average survival of 100 terminal breast cancer patients at Madison before 5-FU was devised, was 13 months. The average survival of 100 such patients treated with 5-FU has been over 29 months.
Brown, Harvard, and Toronto universities. He has held visiting professorships at several universities in India and at these European universities: Amsterdam, Berlin, Heidelberg, Ghent, Vienna, and Rome.
His latest books include "The Genius of the German Lyric," "Medusa's Mirror" (covering topics from medieval German literature to the plays of Hauptmann), "The Harrap Anthology of German Poetry," and "Woge im Westen." He also has contributed articles, reviews, and criticisms to the Contemporary Review, the Times Literary Supplement, and to many other English and American publications.
He and his late wife did many outstanding translations of German epic and lyric poetry. His daughter teaches English at the University of California.
He was born in Austria but is a British citizen. He was educated in Berlin, Vienna, Graz, and London, and has lectured at Sheffield University and at University College, London.
Dance Committee Chosen
The Steering Committee for the KU Relays Dance April 21 was chosen last night by the SUA Board. General chairman is Gary Buller, Buhler junior. Other committee chairmen are Nick Stucky, Buhler junior, tickets; Becky Williamson, Wichita sophomore, decorations; and Fred Dellva, Kansas City sophomore.
STARTS SUNDAY
COME EARLY
FRIDAY And SATURDAY
STAY LATE!
PLUS
cinemaGIC AN ADVENTURE INTO THE 4TH DIMENSION THE ANGRY RED PLANET
Two Bonus Features Sat.
"REVOLT OF THE SLAVES"
And
"A MATTER OF MORALS"
PLUS "REVOLT OF THE SLAVES" And "A MATTER OF MORALS"
SUNDAY
Cont. 2:40 - 4:50 - 7 & 9:10
In your own interests see this picture from the very beginning to the mind-stunning end!
Based on the story "The Turn of the Screw" by HENRY JAMES and co-starring PETER WYNDARDE and MEGS JENKINS with MICHAEL REDGRAVE as "The Uncle"
PAMELA FRANKLIN and MARTIN STEPHENS as "The Innocents"
Screenplay by WILLAM CIRCOLAD and TRUMAN CAPOE
20th Century Fox
Writers
DEBORAH KERR
the Innocents
— ENDS SATURDAY —
7:00 & 10:20 8:30
"MAN IN THE MOON"
8:30 only
Kenneth Moore
Shirley Anne Field
Michael Hordern
STARTS SATURDAY!!
WILLIAM CLIFTON HOLDEN WEBB
in LEO McCAREY'S
SATAN NEVER SLEEPS
The crowning achievement of the man who gave you "Going My Way" and "The Bells Of St. Mary's"
FRANCE NUYEN
Ends Tonight "The 4 Horsemen of the Apocalypse" 6:30 & 9:10
PRODUCED AND DIRECTED BY
LEO MCAREY
SCREENPLAY BY
CLAUDE BINYON
and LEO MCAREY
BASED ON A NOVEL BY
PEARL S. BUCK
CINEMASCOPE
COLOR by DE LUXE
Sat. Mat. 2 p.m.
Eve. 7:00 & 9:15
Sun. Cont. 2:30 - 4:50
7:10 & 9:30