8 Monday, March 7, 1988 / University Daily Kansan Research helps build KU reputation Professor uses computer to study genetics of schizophrenia By Stacy Foster A KU psychology professor's research could help the University of Kansas become one of the leading schizophrenia research centers in the country, the chairman of the psychology department said last week. Kansan staff writer Rue Cromwell, M. Erick Wright distinguished professor of psychology, said the central focus of his research had been on how the brain processed information and the mechanisms that produced schizophrenia. Ruth Jacobson/KANSAN Cromwell has been studying schizophrenia for almost 20 years. He is now studying possible genetic variants related to schizophrenia. The variants are studied to see how the brain processes information. Through his research, Cromwell has found that schizophrenics process information differently than normal people. Cromwell tests these variants in a computer program called COGLAB or cognitive laboratory. The program detects variants that are common in schizophrenics. Two research students are learning the program so it could be used here. The program was first developed at the University of Nebraska by Will Snoalding, one of Cromwell's former students. Ken Sewell, Topeka graduate student, said that they would be giving a demonstration of the program to one of Cromwell's graduate classes today. When the program is perfected it can be used at the Meninger Foundation and the Veterans Administration Hospital in Topeka. Everything you expect in a good hotel except high prices! Cromwell said the tests can detect the genetic characteristics in high risk persons, such as first- Rue Cromwell degree relatives, which are siblings, parents and children Current schizophrenia data suggest that almost 12 percent of the offspring of diagnosed schizophrenics could develop schizophrenic characteristics themselves. his themical role. Cromwell said this figure could be misleading because 83 percent of those offspring show no sign of schizophrenia. They often have exceptional Cromwell said the tests can detect the genetic characteristics in high risk persons, such as first-degree relatives which are siblings, parents and children. abilities and hold occupations that require creative or intellectual talents. The other 17 percent, however, show signs of severe schizophrenic characteristics, he said. "The genetic factor which determines schizophrenia may be a sensitivity factor that can go either way." Cromwell said. Cromwell's work with schizophrenia makes the University's research of the disorder more complete, said Kathleen McCluskey-Fawcett, department chairman of psychology. "Kansas has some recognition because of the work of Dr. Adams, but this will make it more complete with the addition of the behavioral sciences," she said. Adams said Cromwell's work with the behavioral science aspect of the disorder could be used with his study. Ralph Adams, professor of chemistry, has studied the chemical compounds of schizophrenic brains. "We might be able to see some chemical background to the sensory processes that Rue studies, but right now that is something we haven't developed," Adams said. C. R. Snyder, professor and director of clinical psychology, said Cromwell's record for training clinical psychologists was unmatched in the United States. 842-7030 We wish Partner Wisdom success in this endeavor, and expect to receive free pencils and journal paper. 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