University Daily Kansan / Thursday, February 14, 1991
9
Researchers collaborate to aid cancer treatment
Michelle L. Myers/KANSAN
Riley looks at data collected by Nik Chetwyn, pharmacy intern.
2 KU professors improve detection of cancer drugs Bu Benjamin W. Aller
By Benjamin W. Allen Kansan staff writer
Two KU professors compose part of a team that has developed sensitive methods for measuring contagious forms of cancer drugs in blood plasma.
Christopher Riley and John Stobaugh, associate professors of pharmaceutical chemistry, worked together to modify existing materials and produce a method more sensitive than conventional techniques.
The techniques the team uses are modified separation, chemical labeling and detection methods. Center of Biological Research.
"We have taken all the techniques and put them together." Riley said. "That's not trivial. It's a lot of hard work."
Riley said the open atmosphere for collaboration at the center and at the University of Kansas allowed researchers in many disciplines to come together to solve problems.
"We have developed an assay which no one else could." he said.
Stobaugh agreed with Riley that the cooperative atmosphere in Malott Hall made it possible to do the research.
"We're sort of bridging the gap."
Stobaugh said. "We're putting reaction, separation and detection techniques all in one package. You don't find people delving into all these things anywhere else."
Riley and Stobaugh, with the help of Milan Slavik, KU School of Medicine-Wichita oncologist and professor of medicine, use high-performance liquid chromatography with a laser-based detector to measure the concentrations of cancer drugs in patients.
Liquid chromatography is a
process that separates materials by pumping them with a solvent through a small metal column. This column is packed with a compound that the material is chemically attracted to.
The strength of the attraction determines how long each type of material takes to travel through a substance, which in turn identifies the substance.
At the end of the column is a detector that tells the scientist when a material is exiting the column. The particular detector used to look for cancer drugs uses a laser.
plasma, researchers label the cancer drug with a fluorescent material. The drug is then separated from the plasma, and laser chromatography is used to detect the drug.
After extracting a patient's
In laser chromatography, the fluorescent material attached to the drug is excited by a laser shining on it. The fluorescent material then releases the energy imparted to it by the laser in the form of light. This light then can be seen by photoelectric detectors.
"We couldn't be doing some of these things if we couldn't collaborate with some of the other departments." Stobau said.
AIDS awareness, guest artists top Student Senate allocations
Move to distribute free condoms on campus defeated in vote
Bv Michael Christie
Kansan staff writer
Student Senate voted last night to allocate $8,197 for five bills, including ones that are geared to raise AIDS awareness and bring artists to KU.
Senate voted unanimously to allocate $6,100 to bring two artists to the University of Kansas: Wendyoln Brooks, a poet who will conduct a reading April 4 at Hoch Auditorium, and Karen Hutchinson, an award recipient who will perform March 19 at Murphy Hall. Both events are free.
Bill Drummond, Black History Month committee member, spoke in support of the bills.
We have three specialists in Germany, one of the English department," he said.
Brooks is one of the best poets in the United States, he said.
Drummond said Hutchinson was scheduled to give a March performance at the Kennedy Center in New
York City that already had sold out.
"Karen is the only concert pianist of African-American descent," he said. "This is the same program she's doing at the Kennedy Center."
Senate voted unanimously to allocate $1,164 to the Student Senate AIDS task force, primarily to promote AIDS Awareness Week. The team will conduct the construction and display of a bus sign promoting AIDS awareness.
The condoms were to be distributed with pamphlets, and education would be more effective with the condoms, he said.
Mike Moschini, senator and sponsor of the bill, said, "We're trying to make sure that we are not an unintended consequence."
Senate voted to strike part of the bill that would have allocated $650 for mental health services.
But Mike Schreiner, student body president, said condom distribution in the past had resulted in a lot of leftover condoms.
Greg Horan, Environers representative, said Lovett was prominent for his theory that the Earth was like a living organism that could adapt to changes in the same way that animals do.
In other action, Senate voted unanimously to allocate $500 to help pay for biologist James Lovett to lecture at the University on March 26.
He also said that condoms were available in vending machines in the city.
"He's timely, and I think that this is something we should support," he is.
Senate also voted to allocate $172 to Women's Student Union for telecommunications expenses. The finance commission agreed would be given to groups with office space.
Senate also voted to allocate $261 to KU Community Service.
Schreiner said the money would go primarily to promote student partici-
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